A problem with the endocrine feedback system disease. Failure of a gland to stimulate another gland to release hormones (for example, a problem with the hypothalamus can disrupt hormone production in the pituitary gland) A genetic disorder, such as multiple endocrine neoplasia (MEN) or congenital hypothyroidism.
Symptoms of hormonal imbalances in women include :

• Heavy, irregular, or painful periods.
• Osteoporosis (weak, brittle bones)
• Hot flashes and night sweats.
• Vaginal dryness
• Breast tenderness.
• Indigestion
• Constipation and diarrhea
• Acne during or just before menstruation